Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About COVID-19 Vaccines
COVID-19 (coronavirus disease 2019) is an illness caused by a virus. This virus is a coronavirus called SARS-CoV-2. Most people with COVID-19 have mild symptoms, but some people become very sick. You can protect yourself by getting a COVID-19 vaccine. The vaccines might help keep you from getting sick from COVID-19. And if you do get sick, the vaccines can reduce your risk for:
- Needing to go to urgent care or the emergency room
- Getting severe illness
- Being hospitalized
- Dying
- Getting long COVID
It's important to stay up to date with the COVID-19 vaccines. Contact your health care provider if you don't know when you need another vaccine or if you have other questions about the vaccines.
Centers for Disease Control and Prevention
It sits within Infections and Immune System.
The lead U.S. institute for this subject is the National Institute of Allergy and Infectious Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on COVID-19 Vaccines
1,272 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious DiseasesNational Institute of Allergy and Infectious Diseases (NIAID)
- A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of AgeBioNTech SE
- A Phase 1 Study to Evaluate the Safety and Immunogenicity of GC4006A in Healthy AdultsGC Biopharma Corp
- COVICI-SURV: COVID-19 Vaccination Around ICI Start and SurvivalGroupe Hospitalier Pitie-Salpetriere
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 VaccineNational Institute of Allergy and Infectious Diseases (NIAID)
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated AdultsNational Institute of Allergy and Infectious Diseases (NIAID)
Research already completed
- Impact of COVID-19 Vaccines on Cerebrovascular HealthChinese University of Hong Kong
- COVID-19 Vaccine Education at the Point of Testing to Increase Vaccine Uptake in Vulnerable Communities in SE LouisianaXavier University of Louisiana.
- COVID-19 Vaccine Uptake TrialWashington University School of Medicine
- Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in AdultsNational Institute of Allergy and Infectious Diseases (NIAID)
- COVID-19 Vaccines International Pregnancy Exposure RegistryPregistry
- A Phase 2 Trial of the Immunogenicity and Safety of CVXGA Intranasal COVID Vaccine in Healthy AdultsCyanVac LLC
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- COVID-19 VaccinesCenters for Disease Control and Prevention
- Staying Up to Date with COVID-19 VaccinesCenters for Disease Control and Prevention
Related Issues
- Coronavirus Disease 2019 (COVID-19) Vaccine SafetyCenters for Disease Control and Prevention
- Getting Your COVID-19 VaccineCenters for Disease Control and Prevention
- Vaccine Adverse Event Reporting System (VAERS)Department of Health and Human Services
- Vaccines Protect Your CommunityDepartment of Health and Human Services
Statistics and Research
- Bivalent Boosters Block Severe COVID-19National Institutes of Health
- COVID-19 Vaccinations in the United StatesCenters for Disease Control and Prevention
- COVID-19 Vaccines Not Linked With Fertility IssuesNational Institutes of Health
Clinical Trials
- ClinicalTrials.gov: COVID-19 VaccinesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under COVID-19 Vaccines. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for COVID-19 Vaccines, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.