Also called: Bone mass
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Bone Density
Your bones are made of living tissue. To keep them strong, your body breaks down old bone and replaces it with new bone. But when more bone is broken down than replaced, you lose bone density, also called bone mass. Bone density is a measure of the amount of calcium and other minerals in bone. Bones containing more minerals are denser. They tend to be stronger and less likely to fracture (break).
Losing bone density can weaken your bones. In some cases, it can lead to osteoporosis. This is a disease which can make your bones more likely to break. Low bone density that is not low enough to be osteoporosis is sometimes called osteopenia.
Your bones become less dense as you age. Other factors can also make you more likely to lose bone mass, such as:
- A family history of osteoporosis or low bone mass
- Not developing good bone mass when you are young
- Having certain medical conditions, such as: Endocrine diseases
- Certain digestive diseases
- Rheumatoid arthritis
- Certain types of cancer
- HIV
- Anorexia nervosa, a type of eating disorder
- Corticosteroids
- Proton pump inhibitors (which treat GERD)
- Medicines to treat epilepsy
Not everyone who has low bone mass gets osteoporosis, but they are at higher risk for developing it.
A bone density scan is the best way to measure your bone health. It compares your bone density, or mass, to that of a healthy person who is the same age and sex as you are. It can show:
- Whether you have low bone density
- Whether you have osteoporosis, a disease that makes your bones weak
- Your risk for breaking bones
- Whether your osteoporosis treatment is working
To help keep your bones strong and help prevent osteoporosis, the best thing to do is to eat a healthy diet rich in calcium and vitamin D. Getting regular physical activity, limiting alcohol, and not smoking can also help. In some cases, your health care provider may prescribe medicines to prevent osteoporosis.
It sits within Bones, Joints and Muscles.
The lead U.S. institute for this subject is the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Bone Density
1,064 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .Kafrelsheikh University
- High-Intensity Laser Therapy and Physiotherapy for Bone Health in Postmenopausal Women: A Randomized TrialIuliu Hatieganu University of Medicine and Pharmacy
- Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.VA Office of Research and Development
- Role of Estrogen on Skeletal Outcomes in FHAUniversity of Virginia
- Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA StudyJohns Hopkins Bloomberg School of Public Health
- Early Time-Restricted Eating Combined With Exercise in Older AdultsUniversity of Manouba
Research already completed
- Impact of Pilates Exercises on Bone Mineral Density in Breast Cancer Survivors Receiving Hormonal TherapyBenha University
- Osteoporosis Awareness in Chronic Spinal Cord InjuryAfyonkarahisar Health Sciences University
- Finding the Optimal Resistance Training Intensity For Your BonesUniversity of Waterloo
- Therapeutic Prospects of HMG-CoA Reductase Inhibitors, Atorvastatin and Rosuvastatin, in Osteoporotic PatientsAlkufa university\\collage of pharmacy
- Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate ImplantsMinia University
- Alveolar Ridge Splitting With Simvastatin/PRF Composite and Simultaneous Implant PlacementMaruwan Ali Alteer
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Bone Mineral Density Tests: What the Numbers MeanNational Institute of Arthritis and Musculoskeletal and Skin Diseases
- Low Bone DensityBone Health and Osteoporosis Foundation
Diagnosis and Tests
- Bone Density ScanNational Library of Medicine
Related Issues
- Exercise for Your Bone HealthNational Institute of Arthritis and Musculoskeletal and Skin Diseases
- OsteoporosisEndocrine Society
Genetics
- Camurati-Engelmann disease: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Bone DensityNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Bone Density. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Bone Density, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.