Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Bladder Cancer
The bladder is a hollow organ in your lower abdomen that stores urine. Bladder cancer occurs in the lining of the bladder. It is the sixth most common type of cancer in the United States.
Symptoms include:
- Blood in your urine
- A frequent urge to urinate
- Pain when you urinate
- Low back pain
Risk factors for developing bladder cancer include smoking and exposure to certain chemicals in the workplace. People with a family history of bladder cancer or who are older, White, or male have a higher risk.
Treatments for bladder cancer include surgery, radiation therapy, chemotherapy, and biologic therapy. Biologic therapy boosts your body's own ability to fight cancer.
It sits within Cancers and Kidneys and Urinary System.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Bladder Cancer
2,274 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Microfluidic Urinary Exosome-Based Diagnostic Model for Bladder CancerCancer Institute and Hospital, Chinese Academy of Medical Sciences
- Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic CancerAulos Bioscience, Inc.
- Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology AgentsH. Lee Moffitt Cancer Center and Research Institute
- Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT TrialNational Cancer Institute (NCI)
- Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN StudyNational Cancer Institute (NCI)
Research already completed
- Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid TumorsNational Cancer Institute (NCI)
- An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the CancerBristol-Myers Squibb
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Bladder CancerMayo Foundation for Medical Education and Research
- What Is Bladder Cancer?National Cancer Institute
Symptoms
- Bladder Cancer SymptomsNational Cancer Institute
Diagnosis and Tests
- Bladder Cancer DiagnosisNational Cancer Institute
- Bladder Cancer ScreeningNational Cancer Institute
- Bladder Cancer StagesNational Cancer Institute
- Cystoscopy and UreteroscopyNational Institute of Diabetes and Digestive and Kidney Diseases
- Intravenous Pyelogram (IVP)National Library of Medicine
- PDL1 (Immunotherapy) TestsNational Library of Medicine
- UrographyRadiological Society of North America
Treatments and Therapies
- Bladder Cancer TreatmentNational Cancer Institute
- Drugs Approved for Bladder CancerNational Cancer Institute
- Treatment of Bladder Cancer by StageNational Cancer Institute
Prevention and Risk Factors
- Bladder Cancer Causes and Risk FactorsNational Cancer Institute
- Bladder Cancer Risk FactorsAmerican Cancer Society
Living With
- Coping with Bladder CancerNational Cancer Institute
Related Issues
- Artificial Sweeteners and CancerNational Cancer Institute
- Urinary DiversionNational Institute of Diabetes and Digestive and Kidney Diseases
Genetics
- Bladder cancer: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Advances in Bladder Cancer ResearchNational Cancer Institute
- Cancer Stat Facts: Bladder CancerNational Cancer Institute
Clinical Trials
- ClinicalTrials.gov: Ureteral NeoplasmsNational Institutes of Health
- ClinicalTrials.gov: Urethral NeoplasmsNational Institutes of Health
- ClinicalTrials.gov: Urinary Bladder NeoplasmsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Urinary Bladder Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Bladder Cancer, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.