Also called: Dysautonomia
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Autonomic Nervous System Disorders
Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels. When something goes wrong in this system, it can cause serious problems, including:
- Blood pressure problems
- Heart problems
- Trouble with breathing and swallowing
- Erectile dysfunction in men
Autonomic nervous system disorders can occur alone or as the result of another disease, such as Parkinson's disease, alcoholism and diabetes. Problems can affect either part of the system, as in complex regional pain syndromes, or all of the system. Some types are temporary, but many worsen over time. When they affect your breathing or heart function, these disorders can be life-threatening.
Some autonomic nervous system disorders get better when an underlying disease is treated. Often, however, there is no cure. In that case, the goal of treatment is to improve symptoms.
It sits within Brain and Nerves.
The lead U.S. institute for this subject is the National Institute of Neurological Disorders and Stroke.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Autonomic Nervous System Disorders
1,946 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Music Therapy in Parkinson's DiseaseSiegward -M. Elsas
- A Study of ART0380 for the Treatment of Advanced or Metastatic Solid TumorsArtios Pharma Ltd
- Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEADKarolinska Institutet
- Cryotherapy, PGE2, NGF Levels and Pain After Endodontic RetreatmentAlanya Alaaddin Keykubat University
- Remote Monitoring in Progressive Supranuclear Palsy (PSP)Massachusetts General Hospital
- Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot StudyKarolinska Institutet
Research already completed
- Autoimmune Basis for Postural Tachycardia SyndromeUniversity of Oklahoma
- Clinical Laboratory Evaluation of Chronic Autonomic FailureNational Institute of Neurological Disorders and Stroke (NINDS)
- Acute and Chronic Effects of Combined Training on BP in HypertensivesFederal University of Rio Grande do Sul
- Pre-Gene Therapy Study in Parkinson's Disease and Multiple System AtrophyAskBio Inc
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Autonomic NeuropathyMayo Foundation for Medical Education and Research
- Overview of the Autonomic Nervous SystemMerck & Co., Inc.
Learn More
- Recognizing POTS: Learn to Spot This Mysterious ConditionNational Institutes of Health
Diagnosis and Tests
- Autonomic TestingNational Library of Medicine
Genetics
- Autosomal dominant leukodystrophy with autonomic disease: MedlinePlus GeneticsNational Library of Medicine
- Cold-induced sweating syndrome: MedlinePlus GeneticsNational Library of Medicine
- Congenital central hypoventilation syndrome: MedlinePlus GeneticsNational Library of Medicine
- Dopamine beta-hydroxylase deficiency: MedlinePlus GeneticsNational Library of Medicine
- Familial dysautonomia: MedlinePlus GeneticsNational Library of Medicine
- Horner syndrome: MedlinePlus GeneticsNational Library of Medicine
- Multiple system atrophy: MedlinePlus GeneticsNational Library of Medicine
- Orthostatic hypotension: MedlinePlus GeneticsNational Library of Medicine
- Stüve-Wiedemann syndrome: MedlinePlus GeneticsNational Library of Medicine
- Transthyretin amyloidosis: MedlinePlus GeneticsNational Library of Medicine
- Triple A syndrome: MedlinePlus GeneticsNational Library of Medicine
- Tyrosine hydroxylase deficiency: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Autonomic Nervous System DiseasesNational Institutes of Health
- ClinicalTrials.gov: Hypotension, OrthostaticNational Institutes of Health
- ClinicalTrials.gov: Multiple System AtrophyNational Institutes of Health
- ClinicalTrials.gov: Postural Orthostatic Tachycardia SyndromeNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Autonomic Nervous System Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Autonomic Nervous System Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.