Also called: ASD · Pervasive developmental disorder (PDD)
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurological and developmental disorder that begins early in childhood and lasts throughout a person's life. It affects how a person acts and interacts with others, communicates, and learns. It includes what used to be known as Asperger syndrome and pervasive developmental disorders.
It is called a "spectrum" disorder because people with ASD can have a range of symptoms. People with ASD might have problems talking with you, or they might not look you in the eye when you talk to them. They may also have restricted interests and repetitive behaviors. They may spend a lot of time putting things in order, or they may say the same sentence again and again. They may often seem to be in their "own world."
At well-child checkups, the health care provider should check your child's development. If there are signs of ASD, your child will have a comprehensive evaluation. It may include a team of specialists, doing various tests and evaluations to make a diagnosis.
The causes of ASD are not known. Research suggests that both genes and environment play important roles.
There is currently no one standard treatment for ASD. There are many ways to increase your child's ability to grow and learn new skills. Starting them early can lead to better results. Treatments include behavior and communication therapies, skills training, and medicines to control symptoms.
It sits within Children and Teenagers and Mental Health and Behavior.
The lead U.S. institute for this subject is the National Institute of Mental Health.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Autism Spectrum Disorder
2,247 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)Children's Hospital of Orange County
- Developing Brain, Impulsivity and CompulsivityNational Institute of Mental Health (NIMH)
- Perinatal Autism Genetics and Epigenetics StudyUniversity of Iowa
- Role of Omega-DEK in Childhood Apraxia of SpeechClaudia R. Morris
- Studying Childhood-onset Behavioral, Psychiatric, and Developmental DisordersNational Institute of Mental Health (NIMH)
- Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental DisordersHolland Bloorview Kids Rehabilitation Hospital
Research already completed
- Project VOICES: Vocal Optimization in Children Elevating the SpectrumVanderbilt University Medical Center
- Psychoeducation of Adult Siblings of ASD People (Autism Spectrum Disorder).Hellenic Mediterranean University
- Cognitive Neuroscience of Autism Spectrum DisordersNational Institute of Mental Health (NIMH)
- Sensory-Friendly Physical Activity for Sleep in Autistic ChildrenXili Wen
- Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With Autism Spectrum DisorderIntra-Cellular Therapies, Inc.
- Iterative Redesign of a Multifaceted Implementation Strategy for a School-based Behavioral Skills Intervention (RUBI)University of Washington
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- AutismNational Institute of Environmental Health Sciences
- Autism Spectrum DisorderNational Institute of Mental Health
- Autism Spectrum Disorder (ASD)Eunice Kennedy Shriver National Institute of Child Health and Human Development
Learn More
- How Can I Help Someone with Autism?Nemours Foundation
- New Autism DiagnosisAutism Society of America Foundation
Diagnosis and Tests
- Autism Spectrum Disorder (ASD) ScreeningNational Library of Medicine
- PTEN Genetic TestNational Library of Medicine
- Screening and Diagnosis: Identifying Autism
Treatments and Therapies
- Occupational TherapyAutism Speaks
Living With
- Individualized Education Programs (IEPs)Nemours Foundation
- Nutrition for Your Child with Autism Spectrum Disorder (ASD)Academy of Nutrition and Dietetics
Related Issues
- Autism Spectrum Disorder: Communication Problems in ChildrenNational Institute on Deafness and Other Communication Disorders
- Frequently Asked Questions about Autism Spectrum DisorderCenters for Disease Control and Prevention
- Is There a Connection Between Vaccines and Autism?Nemours Foundation
Genetics
- 16p11.2 deletion syndrome: MedlinePlus GeneticsNational Library of Medicine
- About AutismNational Human Genome Research Institute
- ADNP syndrome: MedlinePlus GeneticsNational Library of Medicine
- Autism spectrum disorder: MedlinePlus GeneticsNational Library of Medicine
- MBD5-associated neurodevelopmental disorder: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Data and Statistics on Autism Spectrum DisorderCenters for Disease Control and Prevention
Clinical Trials
- ClinicalTrials.gov: Asperger SyndromeNational Institutes of Health
- ClinicalTrials.gov: Autism Spectrum DisorderNational Institutes of Health
- ClinicalTrials.gov: Autistic DisorderNational Institutes of Health
- ClinicalTrials.gov: Child Development Disorders, PervasiveNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Autism Spectrum Disorder. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Autism Spectrum Disorder, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.