Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Amyloidosis
Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.
There are three main types of amyloidosis:
- Primary - with no known cause
- Secondary - caused by another disease, including some types of cancer
- Familial - passed down through genes
Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.
It sits within Metabolic Problems.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Amyloidosis
1,307 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Amyloid PET Imaging in the Baltimore Longitudinal Study of AgingNational Institute on Aging (NIA)
- The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding AreasMayo Clinic
- Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular HypertrophyAssistance Publique - Hôpitaux de Paris
- Cardiac Magnetic Resonance and Echocardiography Study With AcoramidisEidos Therapeutics, a BridgeBio company
- An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.Yale University
- A Non-interventional Cohort Safety Study of Patients With hATTR-PNAkcea Therapeutics
Research already completed
- N-of-1 for Beta-Blockers in Cardiac AmyloidosisWeill Medical College of Cornell University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- AmyloidosisMayo Foundation for Medical Education and Research
- Amyloidosis and Kidney DiseaseNational Institute of Diabetes and Digestive and Kidney Diseases
- Think Amyloid: A Guide for Understanding AmyloidosisAmerican Society of Nuclear Cardiology
Diagnosis and Tests
- Bone Marrow TestsNational Library of Medicine
- Diagnosis of AmyloidosisMerck & Co., Inc.
- Free Light ChainsNational Library of Medicine
Treatments and Therapies
- Amyloidosis: Diagnosis and TreatmentMayo Foundation for Medical Education and Research
Related Issues
- AL Amyloidosis and Agent OrangeDepartment of Veterans Affairs
- General Information about Plasma Cell Neoplasms (Including Multiple Myeloma)National Cancer Institute
Genetics
- Hereditary cerebral amyloid angiopathy: MedlinePlus GeneticsNational Library of Medicine
- Lattice corneal dystrophy type II: MedlinePlus GeneticsNational Library of Medicine
- Primary localized cutaneous amyloidosis: MedlinePlus GeneticsNational Library of Medicine
- Transthyretin amyloidosis: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: AmyloidosisNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Amyloidosis. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Amyloidosis, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.