Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Advance Directives
What kind of medical care would you want if you were too ill or hurt to express your wishes? Advance directives are legal documents that allow you to spell out your decisions about end-of-life care ahead of time. They give you a way to tell your wishes to family, friends, and health care professionals and to avoid confusion later on.
A living will tells which treatments you want if you are dying or permanently unconscious. You can accept or refuse medical care. You might want to include instructions on:
- The use of dialysis and breathing machines
- If you want to be resuscitated if your breathing or heartbeat stops
- Tube feeding
- Organ or tissue donation
A durable power of attorney for health care is a document that names your health care proxy. Your proxy is someone you trust to make health decisions for you if you are unable to do so.
It sits within Social/Family Issues and Personal Health Issues.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Advance Directives
65 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Mobile Health Application (PACT) to Improve Engagement in Advance Care PlanningFred Hutchinson Cancer Center
- Advance Directive Implementation and Scientific Evaluation StudyUniversity Hospital, Basel, Switzerland
- Project Talk Trial: Engaging Underserved Communities in End-of-life ConversationsMilton S. Hershey Medical Center
- Motivational Interviewing to Enhance Advance Care Planning for Older Adults and Caregivers After Emergency VisitsThe University of Hong Kong
- Advance Choice Document ImplementationKing's College London
- Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2Milton S. Hershey Medical Center
Research already completed
- Web-Based Advance Care Planning for Patients With Advanced CancerTri-Service General Hospital (TSGH)
- Patient Journey in Palliative Care Within the NOVO Hospital Group.Hôpital NOVO
- Survey on Palliative Care and Law PerceptionUniversity of Athens
- Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and SupportIndiana University
- Effect of an Advance Care Planning InterventionBrown University
- UC Health Care Planning StudyUniversity of California, Los Angeles
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Advance Care Planning: Advance Directives for Health CareNational Institute on Aging
- Advance DirectivesNational Cancer Institute
- Advance Directives and Do Not Resuscitate (DNR) OrdersAmerican Academy of Family Physicians
- Living Wills and Advance Directives for Medical DecisionsMayo Foundation for Medical Education and Research
Related Issues
- Advance Care Planning and Health Care Decisions: Tips for Caregivers and FamiliesNational Institute on Aging
- Getting Your Affairs in Order Checklist: Documents to Prepare for the FutureNational Institute on Aging
- Making Decisions for Someone at the End of LifeNational Institute on Aging
- What doctors want patients to know about end-of-life care planningAmerican Medical Association
Clinical Trials
- ClinicalTrials.gov: Advance DirectivesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Advance Directives. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Advance Directives, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.