Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Adrenal Gland Cancer
Your adrenal, or suprarenal, glands are located on the top of each kidney. These glands produce hormones that you can't live without, including sex hormones and cortisol, which helps you respond to stress and has many other functions.
A number of disorders can affect the adrenal glands, including tumors. Tumors can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Most adrenal gland tumors are benign. They usually do not cause symptoms and may not require treatment. Malignant adrenal gland cancers are uncommon.
Types of tumors include:
- Adrenocortical carcinoma - cancer in the outer part of the gland
- Neuroblastoma, a type of childhood cancer
- Pheochromocytoma - a rare tumor that is usually benign
Symptoms depend on the type of cancer you have. Treatments may include surgery, chemotherapy, or radiation therapy.
It sits within Cancers and Endocrine System.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Adrenal Gland Cancer
272 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical CarcinomaNational Cancer Institute (NCI)
- Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump TherapyNational Cancer Institute (NCI)
- Prospective Comprehensive Molecular Analysis of Endocrine NeoplasmsNational Cancer Institute (NCI)
- Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical CancerNational Cancer Institute (NCI)
- EndoSense: Continuous Real-Time Monitoring of Health Markers in Endocrine and Metabolic DisordersFelix Beuschlein
- IDOV-Immune for Advanced Solid TumorsViroMissile, Inc.
Research already completed
- Study of Adrenal Gland TumorsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney ComplexEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- What Is Adrenal Cancer?American Cancer Society
- What Is Adrenocortical Carcinoma?National Cancer Institute
Symptoms
- Signs and Symptoms of Adrenal CancersAmerican Cancer Society
Diagnosis and Tests
- Abdominal and Pelvic CTRadiological Society of North America
- Adrenocortical Carcinoma StagesNational Cancer Institute
- Adrenocorticotropic Hormone (ACTH)National Library of Medicine
- Aldosterone TestNational Library of Medicine
- Body MRIRadiological Society of North America
- Cortisol TestNational Library of Medicine
- DHEA Sulfate TestNational Library of Medicine
- Tests for Adrenal CancerAmerican Cancer Society
- What Causes Adrenal Cancer?American Cancer Society
Treatments and Therapies
- Adrenal Gland Removal (Adrenalectomy)Society of American Gastrointestinal and Endoscopic Surgeons
- Adrenocortical Carcinoma TreatmentNational Cancer Institute
- Questions to Ask about Adrenal CancerAmerican Cancer Society
Living With
- Living as an Adrenal Cancer SurvivorAmerican Cancer Society
Genetics
- Carney Complex (CNC)American Cancer Society
Statistics and Research
- Key Statistics for Adrenal CancerAmerican Cancer Society
Clinical Trials
- ClinicalTrials.gov: Adrenal Gland NeoplasmsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Adrenal Gland Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Adrenal Gland Cancer, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.