What Is Alpha-Gal Syndrome and Why Does It Happen

Alpha-Gal Syndrome (AGS): A food allergy to red meat caused by a tick bite that triggers an immune response to alpha-gal.

Alpha-gal: A sugar molecule found in mammalian meat, such as beef, pork, and lamb.

Tick bite: AGS is triggered by a tick bite, typically from the Lone Star tick.

Delayed reaction: Symptoms occur 3-6 hours after consuming red meat or products containing alpha-gal.

Symptoms: Hives, itching, swelling, stomach pain, diarrhea, vomiting, and anaphylaxis.

Geographic distribution: AGS has been reported in the US, Europe, Australia, and other regions.

Risk factors: Outdoor activities, tick exposure, and adult age increase the risk of developing AGS.

Diagnosis: Blood tests detect alpha-gal antibodies to confirm AGS.

Treatment: Avoiding red meat and products containing alpha-gal, managing symptoms with medications.

Prevention: Preventing tick bites through protective clothing, insect repellents, and regular tick checks can reduce the risk of AGS.

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